GHK-Cu
Symbol Gh · MW 402 Da
Copper-binding tripeptide widely used in skin remodeling and hair products.
- Discovered
- 1973
- Half-life
- 1 hour
- Approval
- Cosmetic ingredient
Quick facts
- Category
- Beauty
- Route
- Topical
- Molecular weight
- 402 Da
- Half-life
- 1 hour
- Discovered
- 1973
- Approval status
- Cosmetic ingredient
Reported effects
- Collagen synthesis
- Skin renewal
- Hair follicle support
Overview
GHK-Cu is one of the most recognized copper peptides in skincare and regenerative cosmetic research. It is a naturally occurring copper complex associated with collagen production, wound repair, inflammation balance, and skin remodeling. In skincare, GHK-Cu is commonly used to improve the appearance of fine lines, wrinkles, skin firmness, elasticity, and texture. It is also popular in hair and scalp formulas, although its most common use is in anti-aging skin products. As a copper peptide, GHK-Cu is valued for its ability to support visible skin repair, smoother texture, and overall skin rejuvenation.
Evidence context
GHK-Cu evidence summary
Human clinical evidence
Human clinical evidence for GHK-Cu may be limited, investigational, region-specific, or unavailable in the local source data. Peptidic avoids treating reported effects as proven clinical outcomes.
Animal, preclinical, or formulation evidence
GHK-Cu is listed in a beauty or cosmetic context, where topical formulation data and ingredient claims should be separated from systemic medical claims.
Status and evidence strength
Peptidic lists the approval status for GHK-Cu as Cosmetic ingredient. The reported effects below are reference fields from the peptide database, not medical promises. Source links are included later on the page when available so readers can continue review from primary or reputable sources.
How it's taken
- Typical Administration
- Topical / Injectable
- Typical Dosage
- Topical cosmetic concentration commonly ranges from 1-2mg.
- Typical Frequency
- Topical once or twice daily; injectable frequency is not standardized
There is no established FDA-approved dosage for this peptide. This information is for educational reference only and should not be treated as medical guidance.
Research sources
Source links included from peer-reviewed literature, clinical records, and medical databases for educational research context on GHK-Cu.
Internal links
Related peptides
Frequently asked questions
What category is GHK-Cu in?
GHK-Cu is listed in the Beauty category on Peptidic.
What route is GHK-Cu associated with?
GHK-Cu is associated with the topical route in the Peptidic database. This is descriptive route context, not a use instruction.
Is GHK-Cu approved?
Peptidic lists the approval status for GHK-Cu as: Cosmetic ingredient. Approval details can vary by indication and jurisdiction.
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For educational purposes only. Many peptides shown are research compounds and not approved for human use in all jurisdictions. Explore the full peptide database, peptide calculator, or peptide tracker.
Last reviewed for educational accuracy: 2026-06-01