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#029BeautyTopical

Matrixyl

Symbol Mx · MW 802 Da

Educational onlyNot medical adviceSource links included

Palmitoyl pentapeptide used in topical anti-wrinkle formulations.

Discovered
2000
Half-life
2-30 minutes
Approval
Cosmetic ingredient

Reported effects

  • Wrinkle reduction
  • Collagen support
  • Skin firmness

Overview

Matrixyl, also known as Palmitoyl Pentapeptide, is a topical signal peptide used in anti-aging skincare products. Signal peptides are designed to support the appearance of collagen production and extracellular matrix repair, which are important for firmness and smoothness. Matrixyl is commonly used in serums, creams, and wrinkle treatments to reduce the appearance of fine lines and improve skin texture over time. It is often positioned as a gentler alternative to harsher anti-aging ingredients. As a beauty peptide, Matrixyl is best known for collagen support, wrinkle reduction, and firmer-looking skin.

How it's taken

Topical
Typical Administration
Topical
Typical Dosage
Common cosmetic-use range is low ppm to several percent depending on raw material concentration and finished formula
Typical Frequency
Once or twice daily

Research sources

Source links included from peer-reviewed literature and trusted medical journal records for this peptide.

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For educational purposes only. Many peptides shown are research compounds and not approved for human use in all jurisdictions.