100%
Back to table
#030BeautyTopical

Argireline

Symbol Ag · MW 889 Da

Educational onlyNot medical adviceSource links included

Acetyl hexapeptide that softens expression-line muscle activity topically.

Discovered
2002
Half-life
5 days
Approval
Cosmetic ingredient

Reported effects

  • Expression line softening
  • Topical use
  • Smoothing

Overview

Argireline, also known as Acetyl Hexapeptide-8, is a topical anti-aging peptide commonly used to reduce the appearance of expression lines and fine wrinkles. It is often compared to Botox in marketing because it targets the look of lines caused by repeated facial movement, but it works much more mildly and topically. Argireline is commonly found in wrinkle serums, eye creams, and facial treatments aimed at the forehead, crow's feet, and smile lines. Its purpose is to help the skin appear smoother, more relaxed, and less creased over time. As a skincare peptide, Argireline is popular for non-invasive wrinkle care and expression-line support.

How it's taken

Topical
Typical Administration
Topical
Typical Dosage
Common cosmetic concentration is 5–10%
Typical Frequency
Once or twice daily

Research sources

Source links included from peer-reviewed literature and trusted medical journal records for this peptide.

Interested in Argireline?

Enter your email and we'll send you a curated list of vendors we trust for sourcing this peptide.

No spam · Unsubscribe anytime

For educational purposes only. Many peptides shown are research compounds and not approved for human use in all jurisdictions.