Palmitoyl Tripeptide-1
Symbol P3 · MW 579 Da
Palmitoylated GHK analog supporting collagen and skin repair.
- Discovered
- 2003
- Half-life
- Unknown
- Approval
- Cosmetic ingredient
Quick facts
- Category
- Beauty
- Route
- Topical
- Molecular weight
- 579 Da
- Half-life
- Unknown
- Discovered
- 2003
- Approval status
- Cosmetic ingredient
Reported effects
- Collagen support
- Skin repair
- Anti-aging
Overview
Palmitoyl Tripeptide-1 is a topical signal peptide used in anti-aging skincare to support the appearance of collagen production, skin firmness, and wrinkle reduction. It is commonly found in peptide serums, facial creams, and firming treatments. Palmitoyl Tripeptide-1 is often paired with other peptides to improve the appearance of elasticity, smoothness, and skin density. It works gradually and is typically used as part of a long-term skincare routine. As a beauty peptide, Palmitoyl Tripeptide-1 is best known for collagen-supporting skincare, fine-line reduction, and firmer-looking skin.
Evidence context
Palmitoyl Tripeptide-1 evidence summary
Human clinical evidence
Human clinical evidence for Palmitoyl Tripeptide-1 may be limited, investigational, region-specific, or unavailable in the local source data. Peptidic avoids treating reported effects as proven clinical outcomes.
Animal, preclinical, or formulation evidence
Palmitoyl Tripeptide-1 is listed in a beauty or cosmetic context, where topical formulation data and ingredient claims should be separated from systemic medical claims.
Status and evidence strength
Peptidic lists the approval status for Palmitoyl Tripeptide-1 as Cosmetic ingredient. The reported effects below are reference fields from the peptide database, not medical promises. Source links are included later on the page when available so readers can continue review from primary or reputable sources.
How it's taken
- Typical Administration
- Topical
- Typical Dosage
- Common cosmetic concentration is 1–5% depending on formulation
- Typical Frequency
- Once or twice daily
There is no established FDA-approved dosage for this peptide. This information is for educational reference only and should not be treated as medical guidance.
Research sources
Source links included from peer-reviewed literature, clinical records, and medical databases for educational research context on Palmitoyl Tripeptide-1.
Internal links
Related peptides
Frequently asked questions
What category is Palmitoyl Tripeptide-1 in?
Palmitoyl Tripeptide-1 is listed in the Beauty category on Peptidic.
What route is Palmitoyl Tripeptide-1 associated with?
Palmitoyl Tripeptide-1 is associated with the topical route in the Peptidic database. This is descriptive route context, not a use instruction.
Is Palmitoyl Tripeptide-1 approved?
Peptidic lists the approval status for Palmitoyl Tripeptide-1 as: Cosmetic ingredient. Approval details can vary by indication and jurisdiction.
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For educational purposes only. Many peptides shown are research compounds and not approved for human use in all jurisdictions. Explore the full peptide database, peptide calculator, or peptide tracker.
Last reviewed for educational accuracy: 2026-06-01