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#035BeautyTopical

Palmitoyl Hexapeptide-12

Symbol Ph · MW 737 Da

Educational onlyNot medical adviceSource links included

Firming cosmetic peptide that mimics elastin signaling.

Discovered
2000
Half-life
Unknown
Approval
Cosmetic ingredient

Reported effects

  • Firming
  • Elastin support
  • Anti-aging

Overview

Palmitoyl Hexapeptide-12 is a topical cosmetic peptide used in anti-aging and skin-firming formulas. It is commonly associated with improving the appearance of elasticity, smoothness, and skin resilience. The palmitoyl component helps make the peptide more compatible with skincare formulations and may improve how it interacts with the skin barrier. Palmitoyl Hexapeptide-12 is often included in products designed for mature, dry, or weakened-looking skin. As a beauty peptide, its main purpose is to support firmer-looking skin, improved texture, and a healthier skin appearance.

How it's taken

Topical
Typical Administration
Topical
Typical Dosage
Common cosmetic concentration is 1–5% depending on formulation
Typical Frequency
Once or twice daily

Research sources

Source links included from peer-reviewed literature and trusted medical journal records for this peptide.

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For educational purposes only. Many peptides shown are research compounds and not approved for human use in all jurisdictions.