Sermorelin
Symbol Sm · MW 3358 Da
Truncated GHRH that stimulates pituitary GH release.
- Discovered
- 1984
- Half-life
- 12 minutes
- Approval
- Compounded clinical use
Reported effects
- GH stimulation
- Sleep quality
- Recovery
Overview
Sermorelin is a synthetic growth hormone-releasing hormone peptide that stimulates the pituitary gland to release natural growth hormone. It is often used in discussions about hormone optimization, recovery, sleep quality, body composition, and age-related GH decline. Compared with longer-acting peptides like CJC-1295 with DAC, Sermorelin has a shorter half-life and more closely mimics natural GH-releasing signals. Its purpose is to support the body's own growth hormone production rather than directly replacing growth hormone. As a hormone peptide, Sermorelin is commonly associated with natural GH stimulation and endocrine support.
How it's taken
- Typical Administration
- Injectable
- Typical Dosage
- No established general wellness dosage; commonly referenced range is 100–500 mcg
- Typical Frequency
- Once daily, commonly before sleep
Research sources
Source links included from peer-reviewed literature and trusted medical journal records for this peptide.
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For educational purposes only. Many peptides shown are research compounds and not approved for human use in all jurisdictions.