MOTS-c
Symbol Mt · MW 2175 Da
Mitochondrial-derived peptide regulating metabolic homeostasis.
- Discovered
- 2015
- Half-life
- 2-4 hours
- Approval
- Not FDA-approved
Reported effects
- Insulin sensitivity
- Endurance
- Mitochondrial health
Overview
MOTS-c is a mitochondrial-derived peptide involved in energy metabolism, metabolic regulation, and cellular stress response. Because mitochondria are responsible for producing cellular energy, MOTS-c is commonly discussed in relation to longevity, exercise performance, insulin sensitivity, and metabolic health. It is studied for its potential role in supporting mitochondrial function and improving the body's response to metabolic stress. MOTS-c is often categorized as a longevity peptide because mitochondrial health is closely connected to aging, energy production, and overall cellular resilience. Its purpose is to support metabolic flexibility, mitochondrial function, and healthy aging research.
How it's taken
- Typical Administration
- Injectable
- Typical Dosage
- No established approved dosage; commonly referenced range is 5–15 mg per injection
- Typical Frequency
- 2–3 times weekly
Research sources
Source links included from peer-reviewed literature and trusted medical journal records for this peptide.
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For educational purposes only. Many peptides shown are research compounds and not approved for human use in all jurisdictions.